Bone Marrow Proteoglycan (PRG2) Antibody
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Catalogue No: abx001972
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US$348.00
(Size: 60 µl)
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Datasheet SDS
PRG2 Antibody is a Rabbit Polyclonal antibody against PRG2. The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Research Articles on Bone Marrow Proteoglycan (PRG2)
| Target | Bone Marrow Proteoglycan (PRG2) |
| Research Area | Infection Immunity, Rheumatology, Dermatology |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to human PRG2 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P13727 (UniProt, ExPASy) |
| UniProt Secondary AC | A6XMW0, B2R5I1, P81448, Q14227, Q6ICT2 |
| UniProt Entry Name | PRG2_HUMAN |
| Gene Symbol | PRG2 |
| GeneID | 5553 |
| NCBI Accession | NP_002719.3 |
| KEGG | hsa:5553 |
| String | 9606.ENSP00000312134 |
| Molecular Weight | Calculated MW: 23 kDa/25 kDa Observed MW: 33 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
