Serine/Threonine-Protein Kinase N2 (PKN2) Antibody

Protein-kinase-C-related kinases (PRKs) are part of the lipid-regulated protein kinases (PKC) which also include liver PAK & PKN. Human PRK1 and PRK2 share structurally similar catalytic domains, but less similar N-terminal regulatory regions suggesting different regulatory domain functions. PRK1 and PRK2, as well as a third member of this family, PRK3, show distinct patterns of expression in adult tissues. Additionally, the serine-threonine kinase PRK2 can be specifically cleaved by caspase-3 (and/or caspase-3-like subfamily members) during apoptosis.

Target	Serine/Threonine-Protein Kinase N2 (PKN2)
Clonality	Monoclonal
Reactivity	Human, Monkey, Mouse, Rat
Tested Applications	ELISA, WB, IHC, FCM
Host	Mouse
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human PRK2 expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q16513 (UniProt, ExPASy)
UniProt Secondary AC	B4DQ21, B4DTP5, B4DVG1, D3DT24, Q08AF4, Q9H1W4
UniProt Entry Name	PKN2_HUMAN
GeneID	5586
KEGG	hsa:5586
String	9606.ENSP00000359552
Molecular Weight	140 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Serine/Threonine-Protein Kinase N2 (PKN2)

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