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5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-1 (PRKAA1) Antibody
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Catalogue No: abx001141
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US$217.50
(Size: 20 µl)
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PRKAA1 Antibody is a Rabbit Polyclonal antibody against PRKAA1. The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Research Articles on 5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-1 (PRKAA1)
| Target | 5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-1 (PRKAA1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/1000 - 1/5000, IHC-P: 1/100 - 1/500, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Synthetic peptide corresponding to PRKAA1. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13131 (UniProt, ExPASy) |
| UniProt Secondary AC | A8MTQ6, B2R7E1, O00286, Q5D0E1, Q86VS1, Q9UNQ4 |
| UniProt Entry Name | AAPK1_HUMAN |
| Gene Symbol | PRKAA1 |
| GeneID | 5562 |
| NCBI Accession | NP_006242.5 |
| KEGG | hsa:5562 |
| String | 9606.ENSP00000346148 |
| Molecular Weight | Calculated MW: 64 kDa Observed MW: 64 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |