PRKAA1 (pT183/T172) Antibody

Catalogue No: abx000479
Price: £220.00
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PRKAA1 (pT183/T172) Antibody

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PRKAA1 (pT183/T172) Antibody is a Rabbit Polyclonal antibody against PRKAA1 (pT183/T172). The protein encoded by this gene belongs to the ser/T protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Target PRKAA1 (pT183/T172)
Reactivity Human, Mouse, Rat
Origin Human
Host Rabbit
Clonality Polyclonal
Tested Applications IHC
Recommended dilutions IHC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding T174/T172 of human PRKAA1.
Purification Affinity purified.
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Molecular Weight 63 kDa
Swiss Prot Q13131
GeneID 5562
Gene Symbol PRKAA1, PRKAA2
Concentration > 1 mg/ml
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Availability Shipped within 5-10 working days.
Note This product is for research use only.

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