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PRKAA1 (pT183 / T172) Antibody

Catalogue No: abx000479
Price: £120.00
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PRKAA1 (pT183 / T172) Antibody

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PRKAA1 (pT183/T172) Antibody is a Rabbit Polyclonal antibody against PRKAA1 (pT183/T172). The protein encoded by this gene belongs to the ser/T protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Target PRKAA1 (pT183/T172)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding T174/T172 of human PRKAA1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q13131 (UniProt, ExPASy) P54646 (UniProt, ExPASy)
UniProt Secondary AC A8MTQ6, B2R7E1, O00286, Q5D0E1, Q86VS1, Q9UNQ4
UniProt Entry Name AAPK1_HUMAN
Gene Symbol PRKAA1, PRKAA2
GeneID 5562
String 9606.ENSP00000346148
Molecular Weight Calculated MW: 64 kDa, 65 kDa, 62 kDa
Observed MW: 64 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on PRKAA1 (pT183 / T172) Antibody

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