Protein Kinase cAMP-Dependent Type II Regulatory Subunit Alpha (PRKAR2A) Antibody

PRKAR2A Antibody is a Rabbit Polyclonal antibody against PRKAR2A. The effects of cAMP in most tissues and cell types are mainly modulated via protein kinase A, a heterotetrameric protein complex consisting of two regulatory ® and two catalytic © subunits. The regulatory subunit of cAMP-dependent protein kinase (PRKAR2A) is one of the regulatory subunits and the gene is located on chromosome region 3p21.3-p21.2. The expression of PRKAR2A is tightly regulated during spermatogenesis, a significant increase in expression of this gene was also found in the human myometrium during pregnancy. This antibody got two bands about 45 kDa and 50-55 kDa in western blotting, and the 50-55kDa may be caused by phosphorylation.

Target	Protein Kinase cAMP-Dependent Type II Regulatory Subunit Alpha (PRKAR2A)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/1000 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-404 of human PKA RIIα (PRKAR2A/PKR2).
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P13861 (UniProt, ExPASy)
UniProt Secondary AC	Q16823, Q9BUB1
UniProt Entry Name	KAP2_HUMAN
Gene Symbol	PRKAR2A
GeneID	5576
NCBI Accession	NP_004148.1
KEGG	hsa:5576
String	9606.ENSP00000265563
Molecular Weight	Calculated MW: 46 kDa Observed MW: 46 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Protein Kinase cAMP-Dependent Type II Regulatory Subunit Alpha (PRKAR2A)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue