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Protein Kinase C Alpha (PRKCA) Antibody

Catalogue No: abx000652
Price: £120.00
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Protein Kinase C Alpha (PRKCA) Antibody Protein Kinase C Alpha (PRKCA) Antibody Protein Kinase C Alpha (PRKCA) Antibody

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PRKCA Antibody is a Rabbit Polyclonal antibody against PRKCA. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.

Target PRKCA
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic peptide. C term -peptide of human PRKCA.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P17252 (UniProt, ExPASy)
UniProt Secondary AC B5BU22, Q15137, Q32M72, Q96RE4
UniProt Entry Name KPCA_HUMAN
Gene Symbol PRKCA
GeneID 5578
KEGG hsa:557
String 9606.ENSP00000408695
Molecular Weight Calculated MW: 76 kDa
Observed MW: 76 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Protein Kinase C Alpha (PRKCA) Antibody

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