Protein Arginine Methyltransferase 8 (PRMT8) Antibody

Protein arginine methylation plays a role in signal transduction, RNA processing, transcriptional regulation, and DNA repair. PRMT8, a protein arginine N-methyltransferase most closely related to PRMT1, methylates the guanidino nitrogens of arginyl residues in some proteins. This protein associates with the plasma membrane following myristoylation and exhibits a brain-specific expression pattern, making it unique within this family of enzymes.

Target	Protein Arginine Methyltransferase 8 (PRMT8)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 344-373 amino acids from the C-terminal region of human PRMT8.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9NR22 (UniProt, ExPASy)
UniProt Secondary AC	B2RDP0, Q8TBJ8
UniProt Entry Name	ANM8_HUMAN
String	9606.ENSP00000372067
Molecular Weight	Calculated MW: 45.3 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse PRMT8.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Protein Arginine Methyltransferase 8 (PRMT8)

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