Vitamin K-Dependent Protein C (PROC) Antibody

PROC Antibody is a Rabbit Polyclonal antibody against PROC. This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009].

Target	Vitamin K-Dependent Protein C (PROC)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 43-300 of human Coagulation Protein C.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P04070 (UniProt, ExPASy)
UniProt Secondary AC	B4DPQ7, Q15189, Q15190, Q16001, Q53S74, Q9UC55
UniProt Entry Name	PROC_HUMAN
Gene Symbol	PROC
GeneID	5624
NCBI Accession	NP_000303.1
KEGG	hsa:5624
String	9606.ENSP00000234071
Molecular Weight	Calculated MW: 52 kDa Observed MW: 50 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Vitamin K-Dependent Protein C (PROC)

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