Prominin 1 (PROM1) Antibody

PROM1 Antibody is a Rabbit Polyclonal antibody against PROM1. This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].

Target	Prominin 1 (PROM1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC, IP
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200, IP: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 179-433 of human CD133.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O43490 (UniProt, ExPASy)
UniProt Secondary AC	Q6SV49, Q6SV50, Q6SV51, Q6SV52, Q6SV53, Q96EN6
UniProt Entry Name	PROM1_HUMAN
Gene Symbol	PROM1
GeneID	8842
OMIM	604365
NCBI Accession	NP_006008.1
HGNC	9454
KEGG	hsa:8842
Ensembl	ENSG00000007062
String	9606.ENSP00000426809
Molecular Weight	Calculated MW: 97 kDa Observed MW: 120 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Prominin 1 (PROM1)

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