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Prostaglandin G/H Synthase 2 / COX-2 (PTGS2) Antibody
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Catalogue No: abx239951
Price:
US$420.50
(Size: 100 µg)
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Datasheet SDS
Prostaglandin G/H Synthase 2 / COX-2 (PTGS2) Antibody is a Mouse Monoclonal antibody for the detection of COX2. Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.
Research Articles on Prostaglandin G/H Synthase 2 / COX-2 (PTGS2)
| Target | Prostaglandin G/H Synthase 2 / COX-2 (PTGS2) |
| Research Area | Enzymes and Kinases, Tumor Immunity, Infection Immunity, Reproductive Science, Pulmonology, Gastroenterology, Hormone Metabolism, Cancer |
| Clonality | Monoclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC |
| Host | Mouse |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/100 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | prostaglandin-endoperoxide synthase 2 |
| Isotype | IgG2a |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P35354 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K802, Q16876 |
| UniProt Entry Name | PGH2_HUMAN |
| Gene Symbol | PTGS2 |
| GeneID | 5743 |
| OMIM | 600262 |
| HGNC | 9605 |
| KEGG | hsa:5743 |
| Ensembl | ENSG00000073756 |
| String | 9606.ENSP00000356438 |
| Molecular Weight | Observed MW: 68 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |