Prostaglandin G/H Synthase 2 / COX-2 (PTGS2) Antibody

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Catalogue No: abx010596
Price: US$420.50
(Size: 100 µg)

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WB analysis of various lysates, using PTGS2 antibody (1/600 dilution).
Prostaglandin G/H Synthase 2 / COX-2 (PTGS2) Antibody Prostaglandin G/H Synthase 2 / COX-2 (PTGS2) Antibody

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Datasheet SDS
Prostaglandin G/H Synthase 2 / COX-2 (PTGS2) Antibody is a Rabbit Polyclonal antibody for the detection of COX2.

COX2 (Prostaglandin G/H synthase 2; PTGS2) mediates the formation of prostaglandins from arachidonate. Its subunit structure is homodimer. The fully N-glycosylated PTGS2 is 72–74 kDa and the aglycosylated is 66 kDa (PMID:19656660 ). It also expresses a band of 39 kDa after unspecific cleavage (PMID:17509125 ). The 50 kDa band of fragmented PTGS2 has also previously been detected in AD brains (PMID:14724276 ).

Target Prostaglandin G/H Synthase 2 / COX-2 (PTGS2)
Research Area Enzymes and Kinases, Tumor Immunity, Infection Immunity, Reproductive Science, Pulmonology, Gastroenterology, Hormone Metabolism, Cancer
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen prostaglandin-endoperoxide synthase 2(prostaglandin G/H synthase and cyclooxygenase)
Isotype IgG
Form Liquid
Purity ≥ 95% (SDS-PAGE)
Purification Purified by immunogen affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Shelf Life 12 months.
UniProt Primary AC P35354 (UniProt, ExPASy)
UniProt Secondary AC A8K802, Q16876
UniProt Entry Name PGH2_HUMAN
Gene Symbol PTGS2
GeneID 5743
OMIM 600262
HGNC 9605
KEGG hsa:5743
Ensembl ENSG00000073756
String 9606.ENSP00000356438
Molecular Weight Observed MW: 50 kDa, 80 kDa
Buffer PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration 2 mg/ml
Availability Shipped within 5-12 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Prostaglandin G/H Synthase 2 / COX-2 (PTGS2)


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