26S Proteasome Non-ATPase Regulatory Subunit 8 (PSMD8) Antibody

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Catalogue No: abx179112
Price: US$391.50
(Size: 100 µl)

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Datasheet SDS
Proteasome 26S Subunit, Non ATPase 8 (PSMD8) Antibody is a Rabbit polyclonal antibody against Human Proteasome 26S Subunit, Non ATPase 8 (PSMD8). The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1.

Target 26S Proteasome Non-ATPase Regulatory Subunit 8 (PSMD8)
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 0.5-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Form Liquid
Purification Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P48556 (UniProt, ExPASy)
UniProt Secondary AC B4DX18, Q6P1L7
UniProt Entry Name PSMD8_HUMAN
Gene Symbol PSMD8
GeneID 5714
KEGG hsa:5714
String 9606.ENSP00000215071
Buffer 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability Shipped within 5-12 working days.
Note This product is for research use only.
Research Articles on 26S Proteasome Non-ATPase Regulatory Subunit 8 (PSMD8)


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