Human Proteasome Subunit Alpha Type 3 (PSMA3) Protein
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Catalogue No: abx073254
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(Size: 5 µg)
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Datasheet SDS
Proteasome Subunit Alpha Type 3 (PSMA3) is a recombinant enzyme. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.
Research Articles on Proteasome Subunit Alpha Type 3 (PSMA3)
| Target | Proteasome Subunit Alpha Type 3 (PSMA3) |
| Research Area | Enzymes and Kinases, Infection Immunity, Hepatology |
| Origin | Human |
| Expression | Recombinant |
| Tested Applications | SDS-PAGE |
| Host | E. coli |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Form | Liquid |
| Activity | Not tested |
| Purity | > 95% (SDS-PAGE) |
| Storage | Store at -20°C for long term storage or at 4°C for up to 1 month. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P25788 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RCK6, Q86U83, Q8N1D8, Q9BS70 |
| UniProt Entry Name | PSA3_HUMAN |
| Gene Symbol | PSMA3 |
| GeneID | 5684 |
| OMIM | 176843 |
| HGNC | 9532 |
| KEGG | hsa:5684 |
| Ensembl | ENSG00000100567 |
| String | 9606.ENSP00000216455 |
| Sequence | MGSSHHHHHH SSGLVPRGSH MSSIGTGYDL SASTFSPDGR VFQVEYAMKA VENSSTAIGI RCKDGVVFGV EKLVLSKLYE EGSNKRLFNV DRHVGMAVAG LLADARSLAD IAREEASNFR SNFGYNIPLK HLADRVAMYV HAYTLYSAVR PFGCSFMLGS YSVNDGAQLY MIDPSGVSYG YWGCAIGKAR QAAKTEIEKL QMKEMTCRDI VKEVAKIIYI VHDEVKDKAF ELELSWVGEL TNGRHEIVPK DIREEAEKYA KESLKEEDES DDDNM |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |