Human Proteasome Subunit Alpha Type 6 (PSMA6) Protein
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Catalogue No: abx073731
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(Size: 2 µg)
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Datasheet SDS
Proteasome Subunit Alpha Type 6 (PSMA6) Subunit Alpha Type 6 is a recombinant enzyme. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome.
Research Articles on Proteasome Subunit Alpha Type 6 (PSMA6)
| Target | Proteasome Subunit Alpha Type 6 (PSMA6) |
| Research Area | Enzymes and Kinases |
| Origin | Human |
| Expression | Recombinant |
| Tested Applications | SDS-PAGE |
| Host | E. coli |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Form | Liquid |
| Activity | Not tested |
| Purity | > 90% (SDS-PAGE) |
| Storage | Store at -20°C for long term storage or at 4°C for up to 1 month. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P60900 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R7J9, B4DQR4, B4DXJ9, P34062, Q6IB60 |
| UniProt Entry Name | PSA6_HUMAN |
| Gene Symbol | PSMA6 |
| GeneID | 5687 |
| OMIM | 602855 |
| HGNC | 9535 |
| KEGG | hsa:5687 |
| Ensembl | ENSG00000100902 |
| String | 9606.ENSP00000261479 |
| Sequence | MGSSHHHHHH SSGLVPRGSH MGSHMSRGSS AGFDRHITIF SPEGRLYQVE YAFKAINQGG LTSVAVRGKD CAVIVTQKKV PDKLLDSSTVTHLFKITENI GCVMTGMTAD SRSQVQRARY EAANWKYKYG YEIPVDMLCK RIADISQVYT QNAEMRPLGC CMILIGIDEE QGPQVYKCDP AGYYCGFKAT AAGVKQTEST SFLEKKVKKK FDWTFEQTVE TAITCLSTVL SIDFKPSEIE VGVVTVENPK FRILTEAEID AHLVALAERD |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |