Proteasome Subunit Beta Type 1 (PSMB1) Antibody (HRP)

Proteasome Subunit Beta Type 1 (PSMB1) Antibody (HRP) is a Rabbit Polyclonal antibody against Proteasome Subunit Beta Type 1 (PSMB1) conjugated to HRP. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species.

Target	Proteasome Subunit Beta Type 1 (PSMB1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA
Host	Rabbit
Recommended dilutions	Optimal dilutions/concentrations should be determined by the end user.
Conjugation	HRP
Immunogen	Recombinant human Proteasome subunit beta type-1 protein (29-241AA).
Isotype	IgG
Form	Liquid
Purity	> 95%
Purification	Purified by Protein G.
Storage	Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P20618 (UniProt, ExPASy)
UniProt Secondary AC	B5BU76, Q9BWA8
UniProt Entry Name	PSB1_HUMAN
Gene Symbol	PSMB1
GeneID	5689
OMIM	602017
HGNC	9537
KEGG	hsa:5689
Ensembl	ENSG00000008018
String	9606.ENSP00000262193
Buffer	0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Proteasome Subunit Beta Type 1 (PSMB1)

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