Human Proteasome Subunit Beta Type 2 (PSMB2) Protein

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Catalogue No: abx073735
Price: US$261.00
(Size: 2 µg)

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Datasheet SDS
Proteasome Subunit Beta Type 2 (PSMB2) is a recombinant enzyme. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Target Proteasome Subunit Beta Type 2 (PSMB2)
Origin Human
Expression Recombinant
Tested Applications SDS-PAGE
Host E. coli
Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
Form Liquid
Activity Not tested
Purity > 90% (SDS-PAGE)
Storage Store at 4 °C if the entire vial will be used within 2-4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles.
UniProt Primary AC P49721 (UniProt, ExPASy)
UniProt Secondary AC D3DPS0, P31145, Q9BWZ9
UniProt Entry Name PSB2_HUMAN
Gene Symbol PSMB2
GeneID 5690
OMIM 602175
HGNC 9539
KEGG hsa:5690
Ensembl ENSG00000126067
String 9606.ENSP00000362334
Sequence MGSSHHHHHH SSGLVPRGSH MEYLIGIQGP DYVLVASDRV AASNIVQMKD DHDKMFKMSE KILLLCVGEA GDTVQFAEYI QKNVQLYKMR NGYELSPTAA ANFTRRNLAD CLRSRTPYHV NLLLAGYDEH EGPALYYMDY LAALAKAPFA AHGYGAFLTL SILDRYYTPT ISRERAVELL RKCLEELQKR FILNLPTFSV RIIDKNGIHD LDNISFPKQG S.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Proteasome Subunit Beta Type 2 (PSMB2)


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