Proteasome Subunit Alpha Type 3 (PSMA3) Antibody

PSMA3 Antibody is a Rabbit Polyclonal antibody against PSMA3. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.

Target	Proteasome Subunit Alpha Type 3 (PSMA3)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IP
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IP: 0.5-4 µg/200-400 µg whole cell extracts. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-255 of human PSMA3.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P25788 (UniProt, ExPASy)
UniProt Secondary AC	B2RCK6, Q86U83, Q8N1D8, Q9BS70
UniProt Entry Name	PSA3_HUMAN
Gene Symbol	PSMA3
GeneID	5684
NCBI Accession	NP_002779.1
KEGG	hsa:5684
String	9606.ENSP00000216455
Molecular Weight	Calculated MW: 28 kDa Observed MW: 28 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Proteasome Subunit Alpha Type 3 (PSMA3)

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