Proteasome Subunit Alpha Type 4 (PSMA4) Antibody

PSMA4 Antibody is a Rabbit Polyclonal antibody against PSMA4. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target	Proteasome Subunit Alpha Type 4 (PSMA4)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC, IP
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200, IP: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-261 of human PSMA4.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P25789 (UniProt, ExPASy)
UniProt Secondary AC	D3DW86, Q53XP2, Q567Q5, Q8TBD1
UniProt Entry Name	PSA4_HUMAN
Gene Symbol	PSMA4
GeneID	5685
NCBI Accession	NP_001096137.1
KEGG	hsa:5685
String	9606.ENSP00000044462
Molecular Weight	Calculated MW: 29 kDa Observed MW: 28 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	0.44 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Proteasome Subunit Alpha Type 4 (PSMA4)

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