+44 (0) 1223 755950
+1 832 327 7413
Proteasome Subunit Beta Type 10 (PSMB10) Antibody
REQUEST MORE INFO
Catalogue No: abx004174
Price:
US$203.00
(Size: 20 µl)
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
PSMB10 Antibody is a Rabbit Polyclonal antibody against PSMB10. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome.
Research Articles on Proteasome Subunit Beta Type 10 (PSMB10)
| Target | Proteasome Subunit Beta Type 10 (PSMB10) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-273 of human PSMB10. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P40306 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R5J4, Q5U098 |
| UniProt Entry Name | PSB10_HUMAN |
| Gene Symbol | PSMB10 |
| GeneID | 5699 |
| NCBI Accession | NP_002792.1 |
| KEGG | hsa:5699 |
| String | 9606.ENSP00000351314 |
| Molecular Weight | Calculated MW: 29 kDa Observed MW: 29 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
