Proteasome Subunit Beta Type 5 (PSMB5) Antibody

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Catalogue No: abx001609
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
PSMB5 Antibody is a Rabbit Polyclonal antibody against PSMB5. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). Multiple transcript variants encoding different isoforms have been found for this gene.

Target Proteasome Subunit Beta Type 5 (PSMB5)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC, IP
Host Rabbit
Recommended dilutions WB: 1/2000 - 1/7000, IHC-P: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200, IP: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-263 of human PSMB5.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P28074 (UniProt, ExPASy)
UniProt Entry Name PSB5_HUMAN
Gene Symbol PSMB5
GeneID 5693
NCBI Accession NP_002788.1
KEGG hsa:5693
String 9606.ENSP00000355325
Molecular Weight Calculated MW: 28 kDa
Observed MW: 22/28 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Proteasome Subunit Beta Type 5 (PSMB5)


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