26S Proteasome Regulatory Subunit 6A (PSMC3) Antibody

Catalogue No: abx001618
Price: £120.00
(Size: 20 µl)
Reviews: 0 reviews
(0 reviews)

Click on the image to see the image legend

Available Options

* Size:




26S Proteasome Regulatory Subunit 6A (PSMC3) Antibody is a Rabbit Polyclonal antibody against 26S Proteasome Regulatory Subunit 6A (PSMC3). The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9.

Target 26S Proteasome Regulatory Subunit 6A (PSMC3)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human PSMC3.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P17980 (UniProt, ExPASy)
UniProt Secondary AC B2R8V1, Q3B757, Q3B865, Q53HU5, Q6GPG8, Q6IBS1, Q96HD3
UniProt Entry Name PRS6A_HUMAN
Gene Symbol PSMC3
GeneID 5702
OMIM 186852
NCBI Accession NM_002804
HGNC 9549
KEGG hsa:5702
Ensembl ENSG00000165916
String 9606.ENSP00000481029
Molecular Weight Calculated MW: 49 kDa
Observed MW: 49 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on 26S Proteasome Regulatory Subunit 6A (PSMC3)

Write a review

Your Name
Your Email Address
PMID
DOI
Your Review

Note: HTML is not translated!

Rating Bad Good

Tags:
(Click to show)