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26S Proteasome Regulatory Subunit 6A (PSMC3) Antibody

Catalogue No: abx001618
Price: £120.00
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26S Proteasome Regulatory Subunit 6A (PSMC3) Antibody 26S Proteasome Regulatory Subunit 6A (PSMC3) Antibody 26S Proteasome Regulatory Subunit 6A (PSMC3) Antibody 26S Proteasome Regulatory Subunit 6A (PSMC3) Antibody 26S Proteasome Regulatory Subunit 6A (PSMC3) Antibody

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26S Proteasome Regulatory Subunit 6A (PSMC3) Antibody is a Rabbit Polyclonal antibody against 26S Proteasome Regulatory Subunit 6A (PSMC3). The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9.

Target 26S Proteasome Regulatory Subunit 6A (PSMC3)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human PSMC3.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P17980 (UniProt, ExPASy)
UniProt Secondary AC B2R8V1, Q3B757, Q3B865, Q53HU5, Q6GPG8, Q6IBS1, Q96HD3
UniProt Entry Name PRS6A_HUMAN
Gene Symbol PSMC3
GeneID 5702
OMIM 186852
NCBI Accession NM_002804
HGNC 9549
KEGG hsa:5702
Ensembl ENSG00000165916
String 9606.ENSP00000481029
Molecular Weight Calculated MW: 49 kDa
Observed MW: 49 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on 26S Proteasome Regulatory Subunit 6A (PSMC3) Antibody

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