26S Proteasome Regulatory Subunit 10B (PSMC6) Antibody (FITC)
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Catalogue No: abx304988
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US$188.50
(Size: 20 µg)
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Datasheet SDS
26S Proteasome Regulatory Subunit 10B (PSMC6) Antibody (FITC) is a Rabbit Polyclonal against 26S Proteasome Regulatory Subunit 10B (PSMC6) conjugated to FITC. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.
Research Articles on 26S Proteasome Regulatory Subunit 10B (PSMC6)
| Target | 26S Proteasome Regulatory Subunit 10B (PSMC6) |
| Research Area | Enzymes and Kinases |
| Clonality | Polyclonal |
| Reactivity | Human |
| Host | Rabbit |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | FITC |
| Excitation/Emission | 499/515 |
| Laser Line | 488 |
| Immunogen | Recombinant human 26S protease regulatory subunit 10B protein (1-260AA). |
| Isotype | IgG |
| Form | Liquid |
| Purity | > 95% |
| Purification | Purified by Protein G chromatography. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P62333 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R975, P49719, Q6IBU3, Q92524 |
| UniProt Entry Name | PRS10_HUMAN |
| Gene Symbol | PSMC6 |
| GeneID | 5706 |
| OMIM | 602708 |
| HGNC | 9553 |
| KEGG | hsa:5706 |
| Ensembl | ENSG00000100519 |
| String | 9606.ENSP00000401802 |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |