26S Proteasome Non-ATPase Regulatory Subunit 11 (PSMD11) Antibody

26S Proteasome Non-ATPase Regulatory Subunit 11 (PSMD11) Antibody is a Rsbbit Policlonal against 26S Proteasome Non-ATPase Regulatory Subunit 11 (PSMD11). The 26S proteasome (PSMD11) is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The protein is a non-ATPase subunit of the 19S regulator.

Target	26S Proteasome Non-ATPase Regulatory Subunit 11 (PSMD11)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 288-317 amino acids from the C-terminal region of human PSMD11.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O00231 (UniProt, ExPASy)
UniProt Secondary AC	A8K3I7, E1P663, O00495, Q53FT5
UniProt Entry Name	PSD11_HUMAN
Gene Symbol	PSMD11
GeneID	5717
OMIM	604449
NCBI Accession	NP_001257411.1 NM_001270482.1
HGNC	9556
KEGG	hsa:5717
Ensembl	ENSG00000108671
String	9606.ENSP00000261712
Molecular Weight	Calculated MW: 47.5 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Rat and Cow PSMD11.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on 26S Proteasome Non-ATPase Regulatory Subunit 11 (PSMD11)

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