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Proteasome 26S Subunit, Non ATPase 2 (PSMD2) Antibody

Catalogue No: abx001625
Price: £120.00
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Proteasome 26S Subunit, Non ATPase 2 (PSMD2) Antibody Proteasome 26S Subunit, Non ATPase 2 (PSMD2) Antibody Proteasome 26S Subunit, Non ATPase 2 (PSMD2) Antibody Proteasome 26S Subunit, Non ATPase 2 (PSMD2) Antibody

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PSMD2 Antibody is a Rabbit Polyclonal antibody against PSMD2. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1. Alternative splicing results in multiple transcript variants of this gene.

Target PSMD2
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human PSMD2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q13200 (UniProt, ExPASy)
UniProt Entry Name PSMD2_HUMAN
Gene Symbol PSMD2
GeneID 5708
KEGG hsa:5708
String 9606.ENSP00000310129
Molecular Weight Calculated MW: 82 kDa, 85 kDa, 100 kDa
Observed MW: 108 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Proteasome 26S Subunit, Non ATPase 2 (PSMD2) Antibody

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