26S Proteasome Non-ATPase Regulatory Subunit 3 (PSMD3) Antibody

Catalogue No: abx002094
Price: £120.00
(Size: 20 µl)
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PSMD3 Antibody is a Rabbit Polyclonal antibody against PSMD3. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S3 family that functions as one of the non-ATPase subunits of the 19S regulator lid. Single nucleotide polymorphisms in this gene are associated with neutrophil count.

Target 26S Proteasome Non-ATPase Regulatory Subunit 3 (PSMD3)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein of human PSMD3.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O43242 (UniProt, ExPASy)
UniProt Secondary AC B3KMW9, B4DT72, Q96EI2, Q9BQA4
UniProt Entry Name PSMD3_HUMAN
Gene Symbol PSMD3
GeneID 5709
OMIM 617676
NCBI Accession NP_002800.2 NM_002809.3
HGNC 9560
KEGG hsa:5709
Ensembl ENSG00000108344
String 9606.ENSP00000264639
Molecular Weight Calculated MW: 41 kDa, 60 kDa
Observed MW: 65 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on 26S Proteasome Non-ATPase Regulatory Subunit 3 (PSMD3)

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