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26S Proteasome Non-ATPase Regulatory Subunit 3 (PSMD3) Antibody

Catalogue No: abx002094
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26S Proteasome Non-ATPase Regulatory Subunit 3 (PSMD3) Antibody 26S Proteasome Non-ATPase Regulatory Subunit 3 (PSMD3) Antibody

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PSMD3 Antibody is a Rabbit Polyclonal antibody against PSMD3. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S3 family that functions as one of the non-ATPase subunits of the 19S regulator lid. Single nucleotide polymorphisms in this gene are associated with neutrophil count.

Target 26S Proteasome Non-ATPase Regulatory Subunit 3 (PSMD3)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein of human PSMD3.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O43242 (UniProt, ExPASy)
UniProt Secondary AC B3KMW9, B4DT72, Q96EI2, Q9BQA4
UniProt Entry Name PSMD3_HUMAN
Gene Symbol PSMD3
GeneID 5709
OMIM 617676
NCBI Accession NP_002800.2 NM_002809.3 [O43242-1]
HGNC 9560
KEGG hsa:5709
Ensembl ENSG00000108344
String 9606.ENSP00000264639
Molecular Weight Calculated MW: 41 kDa, 60 kDa
Observed MW: 65 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on 26S Proteasome Non-ATPase Regulatory Subunit 3 (PSMD3) Antibody

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