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26S Proteasome Non-ATPase Regulatory Subunit 4 (PSMD4) Antibody

Catalogue No: abx000984
Price: £120.00
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PSMD4 Antibody is a Rabbit Polyclonal antibody against PSMD4. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. Pseudogenes have been identified on chromosomes 10 and 21.

Target 26S Proteasome Non-ATPase Regulatory Subunit 4 (PSMD4)
Clonality Polyclonal
Reactivity Human, Mouse, Monkey
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human PSMD4.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P55036 (UniProt, ExPASy)
UniProt Secondary AC D3DV16, Q5VWC5, Q9NS92
UniProt Entry Name PSMD4_HUMAN
Gene Symbol PSMD4
GeneID 5710
OMIM 601648
NCBI Accession NP_002801.1 NM_002810.2 [P55036-1]
HGNC 9561
Ensembl ENSG00000159352
String 9606.ENSP00000357879
Molecular Weight Calculated MW: 28 kDa, 40 kDa
Observed MW: 50 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration 3.25 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on 26S Proteasome Non-ATPase Regulatory Subunit 4 (PSMD4) Antibody

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