26S Proteasome Non-ATPase Regulatory Subunit 7 (PSMD7) Antibody
REQUEST MORE INFO
Catalogue No: abx236893
Price:
US$420.50
(Size: 100 µg)
Orders to United States ship from United States
(
Click on the image to see the image legend
Add to Cart
Buy It Now
GET A QUOTE
Documents
Datasheet SDS
PSMD7 Antibody is a Rabbit Polyclonal against PSMD7. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.
Research Articles on 26S Proteasome Non-ATPase Regulatory Subunit 7 (PSMD7)
| Target | 26S Proteasome Non-ATPase Regulatory Subunit 7 (PSMD7) |
| Research Area | Enzymes and Kinases |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 |
| Isotype | IgG |
| Form | Liquid |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P51665 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DWS9, Q6PKI2, Q96E97 |
| UniProt Entry Name | PSMD7_HUMAN |
| Gene Symbol | PSMD7 |
| GeneID | 5713 |
| OMIM | 157970 |
| HGNC | 9565 |
| KEGG | hsa:5713 |
| Ensembl | ENSG00000103035 |
| String | 9606.ENSP00000219313 |
| Molecular Weight | Observed MW: 38 kDa |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Concentration | 2 mg/ml |
| Availability | Shipped within 5-12 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |