26S Proteasome Non-ATPase Regulatory Subunit 8 (PSMD8) Antibody
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Catalogue No: abx212927
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US$290.00
(Size: 50 µl)
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Datasheet SDS
PSMD8 Antibody is a Rabbit Polyclonal against PSMD8. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1.
Research Articles on 26S Proteasome Non-ATPase Regulatory Subunit 8 (PSMD8)
| Target | 26S Proteasome Non-ATPase Regulatory Subunit 8 (PSMD8) |
| Research Area | Enzymes and Kinases |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, IHC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1/2000 - 1/5000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Fusion protein of human PSMD8. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Antigen Affinity Chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P48556 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DX18, Q6P1L7 |
| UniProt Entry Name | PSMD8_HUMAN |
| Gene Symbol | PSMD8 |
| GeneID | 5714 |
| KEGG | hsa:5714 |
| String | 9606.ENSP00000215071 |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |