Parathyroid Hormone Receptor 1 (PTH1R) Antibody
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Catalogue No: abx011776
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US$427.75
(Size: 100 µl)
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Datasheet SDS
The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.
Research Articles on Parathyroid Hormone Receptor 1 (PTH1R)
| Target | Parathyroid Hormone Receptor 1 (PTH1R) |
| Research Area | Endocrinology |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, IHC, IF/ICC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human PTH1R expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q03431 (UniProt, ExPASy) |
| UniProt Secondary AC | Q2M1U3 |
| UniProt Entry Name | PTH1R_HUMAN |
| Gene Symbol | PTH1R |
| GeneID | 5745 |
| OMIM | 125350 |
| HGNC | 9608 |
| KEGG | hsa:5745 |
| Ensembl | ENSG00000160801 |
| String | 9606.ENSP00000321999 |
| Molecular Weight | 66 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |