Parathyroid Hormone Receptor 1 (PTH1R) Antibody

PTH1R Antibody is a Rabbit Polyclonal antibody against PTH1R. The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010].

Target	Parathyroid Hormone Receptor 1 (PTH1R)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 27-188 of human PTH1R.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q03431 (UniProt, ExPASy)
UniProt Secondary AC	Q2M1U3
UniProt Entry Name	PTH1R_HUMAN
Gene Symbol	PTH1R
GeneID	5745
NCBI Accession	NP_000307.1
KEGG	hsa:5745
String	9606.ENSP00000321999
Molecular Weight	Calculated MW: 66 kDa Observed MW: 66 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Parathyroid Hormone Receptor 1 (PTH1R)

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