Parathyroid Hormone-Related Protein / PTHrP (PTHLH) Antibody

PTHLH Antibody is a Rabbit Polyclonal antibody against PTHLH. The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, in-frame and downstream of the initiator AUG codon, to give rise to nuclear forms of this hormone. [provided by RefSeq, Jul 2008].

Target	Parathyroid Hormone-Related Protein / PTHrP (PTHLH)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 25-175 of human PTHLH.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P12272 (UniProt, ExPASy)
UniProt Secondary AC	Q15251, Q6FH74
UniProt Entry Name	PTHR_HUMAN
Gene Symbol	PTHLH
GeneID	5744
OMIM	168470
NCBI Accession	NP_945315.1
HGNC	9607
KEGG	hsa:5744
Ensembl	ENSG00000087494
Molecular Weight	Calculated MW: 20 kDa Observed MW: 20 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	1.4 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Parathyroid Hormone-Related Protein / PTHrP (PTHLH)

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