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Protein Tyrosine Phosphatase, Non Receptor Type 2 (PTPN2) Antibody
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Catalogue No: abx001496
Price:
US$348.00
(Size: 60 µl)
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PTPN2 Antibody is a Rabbit Polyclonal antibody against PTPN2. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011].
Research Articles on Protein Tyrosine Phosphatase, Non Receptor Type 2 (PTPN2)
| Target | Protein Tyrosine Phosphatase, Non Receptor Type 2 (PTPN2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human PTPN2 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P17706 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K955, A8MXU3, K7ENG3, Q96AU5, Q96HR2 |
| Gene Symbol | PTPN2 |
| GeneID | 5771 |
| NCBI Accession | NP_536348.1 |
| Molecular Weight | Calculated MW: 40 kDa/45 kDa/48 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
