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Protein Tyrosine Phosphatase, Non Receptor Type 2 (PTPN2) Antibody

Catalogue No: abx001496
Price: £120.00
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Protein Tyrosine Phosphatase, Non Receptor Type 2 (PTPN2) Antibody Protein Tyrosine Phosphatase, Non Receptor Type 2 (PTPN2) Antibody Protein Tyrosine Phosphatase, Non Receptor Type 2 (PTPN2) Antibody

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PTPN2 Antibody is a Rabbit Polyclonal antibody against PTPN2. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011].

Target PTPN2
Clonality Polyclonal
Reactivity Human, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human PTPN2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P17706 (UniProt, ExPASy)
UniProt Secondary AC A8K955, A8MXU3, K7ENG3, Q96AU5, Q96HR2
Gene Symbol PTPN2
GeneID 5771
Molecular Weight Calculated MW: 40 kDa, 45 kDa, 48 kDa
Observed MW: 45 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Protein Tyrosine Phosphatase, Non Receptor Type 2 (PTPN2) Antibody

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