Protein Tyrosine Phosphatase, Non Receptor Type 22 (PTPN22) Antibody

Catalogue No: abx001222
Price: £120.00
(Size: 20 µl)
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PTPN22 Antibody is a Rabbit Polyclonal antibody against PTPN22. This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Target PTPN22
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human PTPN22.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9Y2R2 (UniProt, ExPASy)
UniProt Entry Name PTN22_HUMAN
Gene Symbol PTPN22
GeneID 26191
String 9606.ENSP00000352833
Molecular Weight Calculated MW: 20 kDa, 75 kDa, 78 kDa, 85 kDa, 88 kDa, 91 kDa
Observed MW: 107 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on PTPN22

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