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Protein Tyrosine Phosphatase, Non Receptor Type 22 (PTPN22) Antibody

Catalogue No: abx001222
Price: £120.00
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Protein Tyrosine Phosphatase, Non Receptor Type 22 (PTPN22) Antibody

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PTPN22 Antibody is a Rabbit Polyclonal antibody against PTPN22. This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Target PTPN22
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human PTPN22.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9Y2R2 (UniProt, ExPASy)
UniProt Entry Name PTN22_HUMAN
Gene Symbol PTPN22
GeneID 26191
String 9606.ENSP00000352833
Molecular Weight Calculated MW: 20 kDa, 75 kDa, 78 kDa, 85 kDa, 88 kDa, 91 kDa
Observed MW: 107 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Protein Tyrosine Phosphatase, Non Receptor Type 22 (PTPN22) Antibody

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