Protein Tyrosine Phosphatase, Non Receptor Type 3 (PTPN3) Antibody
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Catalogue No: abx004895
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US$217.50
(Size: 20 µl)
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Datasheet SDS
PTPN3 Antibody is a Rabbit Polyclonal antibody against PTPN3. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Research Articles on Protein Tyrosine Phosphatase, Non Receptor Type 3 (PTPN3)
| Target | Protein Tyrosine Phosphatase, Non Receptor Type 3 (PTPN3) |
| Research Area | Signal Transduction |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to PTPN3. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P26045 (UniProt, ExPASy) |
| UniProt Secondary AC | A0AUW9, E7EN99, E9PGU7 |
| UniProt Entry Name | PTN3_HUMAN |
| Gene Symbol | PTPN3 |
| GeneID | 5774 |
| NCBI Accession | NP_001138840.1 |
| KEGG | hsa:5774 |
| String | 9606.ENSP00000363667 |
| Molecular Weight | Calculated MW: 104 kDa Observed MW: 103 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |