Protein Tyrosine Phosphatase, Non Receptor Type 7 (PTPN7) Antibody

Catalogue No: abx002985
Price: £120.00
(Size: 20 µl)
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PTPN7 Antibody is a Rabbit Polyclonal antibody against PTPN7. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene.

Target PTPN7
Clonality Polyclonal
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human PTPN7.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P35236 (UniProt, ExPASy)
UniProt Secondary AC B3KXE1, Q53XK4, Q5SXQ0, Q5SXQ1, Q9BV05
UniProt Entry Name PTN7_HUMAN
Gene Symbol PTPN7
GeneID 5778
KEGG hsa:5778
String 9606.ENSP00000309116
Molecular Weight Calculated MW: 40 kDa, 45 kDa, 52 kDa
Observed MW: 40 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on PTPN7

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