Protein Tyrosine Phosphatase Receptor Type N (PTPRN) Antibody
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Catalogue No: abx028113
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US$326.25
(Size: 80 µl)
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Datasheet SDS
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus.
Research Articles on Protein Tyrosine Phosphatase Receptor Type N (PTPRN)
| Target | Protein Tyrosine Phosphatase Receptor Type N (PTPRN) |
| Research Area | Signal Transduction, Tumor Immunity, Endocrinology, Autoimmunity, Cancer |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 288-316 amino acids from the Central region of human PTPRN. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q16849 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DK12, F5GZS3, Q08319, Q53QD6, Q6NSL1 |
| UniProt Entry Name | PTPRN_HUMAN |
| KEGG | hsa:5798 |
| String | 9606.ENSP00000295718 |
| Molecular Weight | Calculated MW: 106 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |