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Pumilio Homolog 1 (PUM1) Antibody
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Catalogue No: abx033482
Price:
US$326.25
(Size: 80 µl)
Orders to United States ship from United States
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PUM1 is a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. This protein contains a sequence-specific RNA binding domain comprised of eight repeats and N and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of this protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation.
Research Articles on Pumilio Homolog 1 (PUM1)
| Target | Pumilio Homolog 1 (PUM1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 62-91 amino acids from human PUM1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q14671 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K6W4, B4DG92, D3DPN3, E9PCJ0, Q53HH5, Q5VXY7, Q9HAN1 |
| UniProt Entry Name | PUM1_HUMAN |
| Gene Symbol | PUM1 |
| GeneID | 9698 |
| HGNC | 14957 |
| KEGG | hsa:9698 |
| Ensembl | ENSG00000134644 |
| String | 9606.ENSP00000391723 |
| Molecular Weight | Calculated MW: 126 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Chicken and Xenopus PUM1. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |