Pumilio RNA Binding Family Member 2 (PUM2) Antibody
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Catalogue No: abx033481
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US$326.25
(Size: 80 µl)
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Datasheet SDS
PUM2 is a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. This protein contains a sequence-specific RNA binding domain comprised of eight repeats and N and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of this protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation.
Research Articles on Pumilio RNA Binding Family Member 2 (PUM2)
| Target | Pumilio RNA Binding Family Member 2 (PUM2) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 133-162 amino acids from the N-terminal region of human PUM2. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q8TB72 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KSL0, B4E2B6, D6W527, O00234, Q53TV7, Q8WY43, Q9HAN2 |
| UniProt Entry Name | PUM2_HUMAN |
| Gene Symbol | PUM2 |
| KEGG | hsa:23369 |
| String | 9606.ENSP00000338173 |
| Molecular Weight | Calculated MW: 114 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |