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Poliovirus Receptor Related Protein 1 (PVRL1) Antibody

Catalogue No: abx001654
Price: £120.00
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Poliovirus Receptor Related Protein 1 (PVRL1) Antibody

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PVRL1 Antibody is a Rabbit Polyclonal antibody against PVRL1. This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq, Oct 2009].

Target PVRL1
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human PVRL1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q15223 (UniProt, ExPASy)
UniProt Secondary AC O75465, Q2M3D3, Q9HBE6, Q9HBW2
UniProt Entry Name NECT1_HUMAN
Gene Symbol NECTIN1
GeneID 5818
KEGG hsa:5818
String 9606.ENSP00000264025
Molecular Weight Calculated MW: 39 kDa, 50 kDa, 57 kDa
Observed MW: 55 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Poliovirus Receptor Related Protein 1 (PVRL1) Antibody

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