Poliovirus Receptor Related Protein 2 (PVRL2) Antibody

PVRL2 Antibody is a Rabbit Polyclonal antibody against PVRL2. This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Target	Poliovirus Receptor Related Protein 2 (PVRL2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 382-479 of human Nectin 2/CD112.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q92692 (UniProt, ExPASy)
UniProt Secondary AC	A8K5L5, O75455, Q6IBI6, Q96J29
UniProt Entry Name	NECT2_HUMAN
Gene Symbol	NECTIN2
GeneID	5819
NCBI Accession	NP_002847.1
KEGG	hsa:5819
String	9606.ENSP00000252483
Molecular Weight	Calculated MW: 58 kDa Observed MW: 72 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Poliovirus Receptor Related Protein 2 (PVRL2)

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