Quinolinate Phosphoribosyltransferase (QPRT) Antibody
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Catalogue No: abx028016
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US$326.25
(Size: 80 µl)
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Datasheet SDS
This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease.
Research Articles on Quinolinate Phosphoribosyltransferase (QPRT)
| Target | Quinolinate Phosphoribosyltransferase (QPRT) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 206-234 amino acids from the C-terminal region of human QPRT. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q15274 (UniProt, ExPASy) |
| UniProt Secondary AC | Q53XW7, Q96G22, Q9BSG6 |
| UniProt Entry Name | NADC_HUMAN |
| KEGG | hsa:23475 |
| String | 9606.ENSP00000378782 |
| Molecular Weight | Calculated MW: 30.8 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |