RAB25, Member RAS Oncogene Family (Rab25) Antibody

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Catalogue No: abx011140
Price: US$420.50
(Size: 100 µl)

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Datasheet SDS
Members of the Ras-related superfamily of GTP binding proteins, which includes Ras, Rho, Rab and ARF subfamilies, exhibit 30-50% similarity with Ras p21. Rab proteins play an important role for either in endocytosis or in biosynthetic protein transport. The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the SEC4 protein, which is 40% similar to Rab proteins, is associated with secretory vesicles. Rab proteins located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Rab25 was cloned from a gastric parietal cell cDNA library and is expressed in epithelial tissues such as the gastrointestinal mucosae, kidney, and lung, which encoded a protein of 28 kDa.

Target RAB25, Member RAS Oncogene Family (Rab25)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, IHC
Host Mouse
Recommended dilutions ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of Rab25 expressed in E. coli.
Isotype IgG2a
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P57735 (UniProt, ExPASy)
UniProt Secondary AC Q5VYA2, Q8NG24, Q96GB1, Q9BT12
UniProt Entry Name RAB25_HUMAN
Gene Symbol RAB25
GeneID 57111
OMIM 612942
HGNC 18238
KEGG hsa:57111
Ensembl ENSG00000132698
String 9606.ENSP00000354376
Molecular Weight 24 kDa
Buffer Ascitic fluid containing 0.03% sodium azide.
Concentration Not determined.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on RAB25, Member RAS Oncogene Family (Rab25)


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