RAB7A, Member RAS Oncogene Family (RAB7A) Antibody

RAB7A Antibody is a Rabbit Polyclonal antibody against RAB7A. RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.

Target	RAB7A, Member RAS Oncogene Family (RAB7A)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 100-207 of human RAB7.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P51149 (UniProt, ExPASy)
UniProt Secondary AC	A8K3V6, Q9NWJ0, Q9UPB0
UniProt Entry Name	RAB7A_HUMAN
Gene Symbol	RAB7A
GeneID	7879
NCBI Accession	NP_004628.4
KEGG	hsa:7879
String	9606.ENSP00000265062
Molecular Weight	Calculated MW: 23 kDa Observed MW: 23 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on RAB7A, Member RAS Oncogene Family (RAB7A)

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