RAD51 Recombinase (RAD51) Antibody
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Catalogue No: abx004788
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US$348.00
(Size: 60 µl)
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Datasheet SDS
RAD51 Antibody is a Rabbit Polyclonal antibody against RAD51. The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene.
Research Articles on RAD51 Recombinase (RAD51)
| Target | RAD51 Recombinase (RAD51) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to human RAD51 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | Q06609 (UniProt, ExPASy) |
| UniProt Secondary AC | B0FXP0, B2R8T6, Q6FHX9, Q6ZNA8, Q9BV60 |
| UniProt Entry Name | RAD51_HUMAN |
| Gene Symbol | RAD51 |
| GeneID | 5888 |
| NCBI Accession | NP_002866.2 |
| KEGG | hsa:5888 |
| Molecular Weight | Calculated MW: 26 kDa/31 kDa/36 kDa Observed MW: 37 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
