Receptor Activity Modifying Protein 2 (RAMP2) Antibody

Catalogue No: abx002216
Price: £120.00
(Size: 20 µl)
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Receptor Activity Modifying Protein 2 (RAMP2) Antibody

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RAMP2 Antibody is a Rabbit Polyclonal antibody against RAMP2. The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface.

Target RAMP2
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human RAMP2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O60895 (UniProt, ExPASy)
UniProt Secondary AC A7L9S6, K7EMD3, Q8N1F2
UniProt Entry Name RAMP2_HUMAN
Gene Symbol RAMP2
GeneID 10266
KEGG hsa:10266
String 9606.ENSP00000253796
Molecular Weight Calculated MW: 19 kDa, 20 kDa
Observed MW: 15 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Receptor Activity Modifying Protein 2 (RAMP2) Antibody

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