Receptor Activity Modifying Protein 2 (RAMP2) Antibody
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Catalogue No: abx002216
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US$217.50
(Size: 20 µl)
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Datasheet SDS
RAMP2 Antibody is a Rabbit Polyclonal antibody against RAMP2. The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface.
Research Articles on Receptor Activity Modifying Protein 2 (RAMP2)
| Target | Receptor Activity Modifying Protein 2 (RAMP2) |
| Research Area | Cellular Differentiation and Adhesion |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein corresponding to RAMP2. The exact sequence is proprietary. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O60895 (UniProt, ExPASy) |
| UniProt Secondary AC | A7L9S6, K7EMD3, Q8N1F2 |
| UniProt Entry Name | RAMP2_HUMAN |
| Gene Symbol | RAMP2 |
| GeneID | 10266 |
| NCBI Accession | NP_005845.2 |
| KEGG | hsa:10266 |
| String | 9606.ENSP00000253796 |
| Molecular Weight | Calculated MW: 20 kDa Observed MW: 15 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |