RAMP3 Antibody is a Rabbit Polyclonal antibody against RAMP3. The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor.

Target	Receptor Activity Modifying Protein 3 (RAMP3)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	IF/ICC
Host	Rabbit
Recommended dilutions	IF/ICC: 1/10 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein corresponding to human RAMP3
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O60896 (UniProt, ExPASy)
UniProt Secondary AC	Q7Z2Y1
UniProt Entry Name	RAMP3_HUMAN
Gene Symbol	RAMP3
GeneID	10268
NCBI Accession	NP_005847.1
KEGG	hsa:10268
String	9606.ENSP00000242249
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	1 mg/ml
Availability	Shipped within 5-10 working days.
Note	THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Research Articles on Receptor Activity Modifying Protein 3 (RAMP3)

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