Ras-Related Protein Rap-1A (RAP1A) Antibody

The product of this gene belongs to the family of RAS-related proteins.These proteins share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common.The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins.The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner.Two transcript variants encoding the same protein have been identified for this gene.

Target	Ras-Related Protein Rap-1A (RAP1A)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, FCM
Host	Mouse
Recommended dilutions	ELISA: 1/10000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human RAP1A expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Purified from ascites by Protein G chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P62834 (UniProt, ExPASy)
UniProt Secondary AC	P10113
UniProt Entry Name	RAP1A_HUMAN
Gene Symbol	RAP1A
GeneID	5906
OMIM	179520
HGNC	9855
KEGG	hsa:5906
Ensembl	ENSG00000116473
String	9606.ENSP00000358723
Molecular Weight	43.2 kDa
Buffer	PBS, containing 0.05% sodium azide.
Concentration	1 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Ras-Related Protein Rap-1A (RAP1A)

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