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Ras-Related Protein Rap-1A (RAP1A) Antibody

Catalogue No: abx000928
Price: £120.00
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RAP1A Antibody is a Rabbit Polyclonal antibody against RAP1A. This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants.

Target RAP1A
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human RAP1A.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P62834 (UniProt, ExPASy)
UniProt Secondary AC P10113
UniProt Entry Name RAP1A_HUMAN
Gene Symbol RAP1A
GeneID 5906
KEGG hsa:590
String 9606.ENSP00000358723
Molecular Weight Calculated MW: 20 kDa
Observed MW: 21 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Ras-Related Protein Rap-1A (RAP1A) Antibody

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