RAP2A, Member of RAS Oncogene Family (RAP2A) Antibody

Catalogue No: abx002039
Price: £120.00
(Size: 20 µl)
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RAP2A Antibody is a Rabbit Polyclonal antibody against RAP2A. Ras oncogenes encode GTP-binding proteins that are capable of transforming immortalized cells in culture. Two Ras-related human genes, designated RAP1A and RAP1B, encode 95% homologous proteins (namely Rap 1A and Rap 1B) that share a similar C-terminal Cys-Ali-Ali-Xaa sequence with Ras proteins and are ubiquitously expressed in mammalian tissues. The putative effector domain of Ras proteins, whose integrity is required for cell transformation as well as interaction with the putative effector protein GAP, is conserved in both Rap 1 proteins. Rap 1A is thought to interfere with Ras effector function by binding to Ras GAP in a GTP-dependent manner without affecting Rap 1A GTPase activity. Rap 2, another Ras-related protein, shares 60% identity with Rap 1A and exhibits a carboxy terminal CAAX motif and two upstream cysteines similar to those of the H-Ras, K-Ras and N-Ras proteins. In contrast with Rap 1A and Rap 1B, overexpression of Rap 2 does not interfere with the Ras signaling pathway..

Target RAP2A
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein of human RAP2A.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P10114 (UniProt, ExPASy)
UniProt Secondary AC B2RCJ1, Q5JSC1, Q5JSC2
UniProt Entry Name RAP2A_HUMAN
Gene Symbol RAP2A
GeneID 5911
KEGG hsa:5911
String 9606.ENSP00000245304
Molecular Weight Calculated MW: 20 kDa
Observed MW: 21 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on RAP2A, Member of RAS Oncogene Family (RAP2A) Antibody

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