RasGAP-Activating-Like Protein 1 (RASAL1) Antibody
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Catalogue No: abx026830
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US$326.25
(Size: 80 µl)
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Datasheet SDS
The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described.
Research Articles on RasGAP-Activating-Like Protein 1 (RASAL1)
| Target | RasGAP-Activating-Like Protein 1 (RASAL1) |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 309-337 amino acids from the Central region of human RASAL1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O95294 (UniProt, ExPASy) |
| UniProt Secondary AC | B7ZKM4, C9JFK5, F8VQX1, Q52M03, Q59H24, Q96CC7 |
| UniProt Entry Name | RASL1_HUMAN |
| Gene Symbol | RASAL1 |
| KEGG | hsa:8437 |
| String | 9606.ENSP00000450244 |
| Molecular Weight | Calculated MW: 90 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |